Good Cholesterol VS Bad Cholesterol… Keeping the Balance in Check

September is National Cholesterol Education Month

Cholesterol is a lipid, or fat, essential for the proper functioning of the body. It is a structural component of cell membranes and serves as a precursor for synthesizing various hormones and molecules. Cholesterol is transported through the bloodstream in the form of lipoproteins, which are particles composed of both lipids and proteins. Two main types of lipoproteins carry cholesterol: low-density lipoprotein (LDL) and high-density lipoprotein (HDL).

1. Low-Density Lipoprotein (LDL):
LDL cholesterol is often referred to as “bad” cholesterol. High levels of LDL cholesterol in the blood can lead to cholesterol accumulation in the arteries’ walls, a process known as atherosclerosis. Atherosclerosis can result in the narrowing and hardening of arteries, increasing the risk of heart disease and stroke. LDL cholesterol carries cholesterol from the liver to various cells and tissues in the body, but when present in excess, it can contribute to plaque formation in arteries.

2. High-Density Lipoprotein (HDL):
HDL cholesterol is often referred to as “good” cholesterol. HDL particles have a higher proportion of protein compared to LDL particles. HDL plays a crucial role in reverse cholesterol transport, which involves transporting excess cholesterol from peripheral tissues back to the liver for processing and elimination. Higher HDL cholesterol levels are associated with a reduced risk of heart disease. HDL helps remove cholesterol from the arterial walls, thereby promoting cardiovascular health.

It’s important to note that the LDL to HDL cholesterol ratio is a key indicator of cardiovascular risk. A higher LDL to HDL cholesterol ratio is generally associated with an increased risk of heart disease, while a lower ratio indicates a healthier cardiovascular profile.

While understanding the distinction between LDL and HDL cholesterol is important, consulting with a medical provider is essential to accurately interpret cholesterol levels and assess overall cardiovascular risk. Medical professionals can provide personalized recommendations based on an individual’s medical history, lifestyle, and other risk factors.

To maintain optimal cardiovascular health, individuals are advised to adopt a heart-healthy lifestyle, which includes:

. Eating a balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats.
. Engaging in regular physical activity to help manage weight, improve cardiovascular fitness, and promote overall well-being.
. Avoiding smoking and limiting alcohol consumption.
. Managing conditions such as diabetes, high blood pressure, and obesity, as these can contribute to an increased risk of heart disease.

The difference between good cholesterol (HDL) and bad cholesterol (LDL) lies in their respective roles in cardiovascular health. HDL helps remove excess cholesterol from the body, reducing the risk of heart disease, while LDL can contribute to the formation of arterial plaque, increasing the risk of cardiovascular problems. However, interpreting cholesterol levels and determining the appropriate course of action should be done in consultation with a medical provider, who can offer personalized advice and guidance based on individual health considerations.

Leqvio, also known by its generic name inclisiran, is a medication used to treat high cholesterol levels in individuals who have not effectively responded to dietary changes and other therapies. It is specifically designed to target low-density lipoprotein cholesterol (LDL-C), commonly referred to as “bad” cholesterol. Leqvio is administered as an injection, not an infusion, and it belongs to a class of drugs known as PCSK9 inhibitors.

Mechanism of Action:
Leqvio works by inhibiting the protein PCSK9 (proprotein convertase subtilisin/kexin type 9), which regulates the number of LDL receptors on the surface of liver cells. These receptors are responsible for removing LDL cholesterol from the bloodstream. By inhibiting PCSK9, Leqvio increases the number of available LDL receptors, leading to increased removal of LDL cholesterol from the blood and resulting in lowered LDL-C levels.

Dosage and Frequency:
The dosing regimen for Leqvio involves two doses per year. This extended dosing interval sets it apart from other cholesterol-lowering medications, which may require more frequent dosing. The injections are spaced several months apart to reduce LDL cholesterol levels over time consistently.

Effectiveness:
Clinical trials have shown that Leqvio can significantly lower LDL cholesterol levels when used in conjunction with a healthy diet and other lipid-lowering therapies. It has been demonstrated to be effective in patients with high cholesterol who have not achieved their target LDL-C levels through other treatment options.

Considerations:
As with any medication, there are potential side effects and considerations to keep in mind when using Leqvio. Common side effects may include pain, redness, or swelling at the injection site. Patients need to discuss their medical history and any other medications they are taking with their healthcare provider before starting Leqvio to ensure no potential interactions or contraindications.

Medical Guidance:
Leqvio is a prescription medication; a healthcare professional should oversee its use. Patients who are interested in Leqvio should discuss with their healthcare provider to determine if it’s an appropriate treatment option based on their individual medical history, current health status, and cholesterol management goals.

Sage Infusion Can Help
At Sage Infusion, we provide expert patient-centered infusion care in a contemporary boutique environment. Sage Infusion eases your medical burdens by handling the care coordination process, including insurance authorization and patient progress updates. Our flexible scheduling meets our patient’s needs with extended hours. Day, night, and weekend appointments are available. Our physician assistants and nurse practitioners follow the National Infusion Center Association guidelines and our proprietary clinical protocols. Sage Infusion offers a variety of comforting amenities, and patients can choose to receive treatment in the open lounge or private room.

With locations in The Villages – Lake Sumter, Fort Myers, Clearwater, Orlando, Sarasota, and Tampa. Sage Infusion offers the best infusion and administration facilities in the Sunshine State. At Sage Infusion, we’ve reimagined patient care. From a quick start, to upfront pricing and financial assistance to compassionate care by our clinical experts in a serene environment, you will experience infusion therapy like never before.

Sage Infusion
352-565-5553
sageinfusion.com/swwellness
910 Old Camp Road, Suite 196, The Villages, FL 32162